Alliance Sites Present Positive Results from Placebo Response Initiative

Alliance Sites Present Positive Results from Placebo Response Initiative

Two of the Alliance sites, Hassman Research Institute (HRI) and Collaborative Neuroscience Network (CNS), collaborated to develop a self-funded empirical investigation assessing how a Placebo-Control Reminder Script (PCRS) educating subjects about key factors associated with placebo response in clinical trials might help manage this insidious effect within our industry. They presented their positive results at this year’s CNS Summit, which generally showed that subjects in a major depressive episode who were read the PCRS had significantly less response (p=.01) when receiving a placebo (i.e., stayed more depressed) as compared to subjects who were not read the script. Given our Alliance sites’ continued passion for exploring ways to manage the placebo effect, HRI and CNS plan to commence Part B of the study – using the same methodology with Schizophrenia subjects.

Download the PCRS poster.