• We strive to achieve the highest quality possible for the benefit of subjects and sponsors

  • Established, independent sites exchanging expertise and sharing a business development team

  • Seasoned dedicated research professionals, regulatory and recruitment staff, and sponsor relations team

  • Allied research sites and services in California, Texas, Florida, New Mexico, Colorado, New Jersey, North Carolina, West Virginia, and Oregon

About Us

Founded in 2000, Clinical Trial Centers Alliance is the business development and sponsor relations team for a group of independently owned and operated trial sites and complementary service providers. We provide the advantage of a single point of contact throughout the site selection process as well as single budget and contract negotiation for multiple sites. Operational and therapeutic expertise is shared among members to foster a culture of quality focused on the swift execution of trials while adhering to the highest standards of regulatory compliance, subject safety, and data integrity.

Clinical Research Sites

With seasoned research professionals and regulatory and recruitment staff, Alliance sites have the knowledge and experience to successfully execute your phase I-IV inpatient and outpatient clinical studies. All use a Central IRB.

Our Clinical Trial Experience

Alliance sites have vast experience across a broad range of therapeutic areas.

  • Psychiatry: ADHD, anxiety, bipolar disorder, cognition, depression, PTSD, schizophrenia
  • Neurology: Alzheimer’s, multiple sclerosis, Parkinson’s, post-stroke
  • Sleep: chronic insomnia, excessive daytime sleepiness, narcolepsy, obstructed sleep apnea, polysomnography (PSG), restless legs syndrome (RLS), sleep maintenance
  • Pain: acute, chronic, fibromyalgia, migraine, neuropathic, osteoarthritis, post-surgical, pain modeling
  • Addictions: alcohol, binge eating, drug, opioid, smoking cessation
  • Medical: cardiology, endocrinology, gastrointestinal, immunology, infectious diseases, metabolic disorders, pulmonology, renal/hepatic, women’s health
  • Dermatology: acne, atopic dermatitis, melanoma, psoriasis, rosacea, skin infections
  • Ophthalmology: cataract, conjunctivitis, dry eye syndrome, glaucoma, macular degeneration
  • Specialty and Early Phase: Asian Bridging, driving impairment, Human Abuse Liability (HAL), healthy subjects, bioequivalence, rare/orphan diseases, device and product validation including digital therapies

Clinical Research Services

Our alliance includes complementary services to provide full solutions to run clinical programs.

  • Driving study solutions and more from our affiliated resource, Cognitive Research Corporation
  • Clinical assessments and trial services such as rater training, data management, consulting, and language services from our affiliated resource, VeraSci

Catch up on the latest Alliance news

Download the Alliance fact sheet

Download a presentation about us

Connect with us during these conferences


The Alliance is a division of Apex Innovative Sciences, an industry-leading independent provider of clinical development and trial site services. Apex was formed in 2019 through the merger of CNS Research, Hassman Research Institute, and Clinical Trial Centers Alliance.


Apex Early Phase (AEP) is a specialty division of Apex dedicated to meeting the complex needs inherent in early-stage drug development.